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计算机模拟技术能够可视化主动脉夹层(AD)的血液流动、壁应力分布、真假腔的动态相互作用等临床关注的病理变化过程,从而弥补了传统影像学技术在力学层面分析疾病动态变化的不足。该文综述了当前AD研究中主要的计算机模拟方法,探讨了这些方法在AD发生、发展机制及血管腔内治疗过程中的应用,重点关注其在提升临床决策支持和改善患者预后方面的作用,分析该领域面临的挑战,并对其未来发展进行展望,为推动多学科协作及主动脉夹层研究和治疗的进一步发展提供参考。
Abstract:Computer simulation technology can visualize the pathological changes of clinical concern,including blood flow,wall stress distribution,dynamic interaction between true lumen and false lumen,etc.,in aortic dissection(AD),thus making up for the shortcomings of traditional imaging techniques in analyzing the dynamic changes of diseases at the mechanical level.This article reviews the main computer simulation methods in the current AD research,discusses the application of these methods in the occurrence of AD,development mechanism,and endovascular treatment,focusing on its role in improving clinical decision support and improving patient prognosis.The challenges faced in this field are analyzed,and prospects for its future development are discussed,aiming to provide reference for promoting multidisciplinary collaboration and further development of AD research and treatment.
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基本信息:
中图分类号:TP391.9;R543.1
引用信息:
[1]李智,陆清声.主动脉夹层的计算机模拟研究进展[J].介入放射学杂志,2026,35(05):469-474.
基金信息:
国家自然科学基金(82270510); 上海市2023年度“科技创新行动计划”优秀学术/技术带头人项目基金(23XD1405000); 上海市领军人才(2019LJ17)
2026-05-19
2026-05-19